The new results and the desired shift to free issue that increased drug-resistant bugs. The
bacterium Escherichia coli (E. coli) exposed to repeated cycles of antibiotics not only
survive but also started to breed faster. After eight sessions of treatment in the four-day
bug form three times greater population that will be successful without the drug.
E. coli is a common germ that contaminated food and water and can cause severe stomach
cramps, diarrhea and kidney failure.
Leading scientist Professor Robert Beardmore, of the University of Exeter, said: "our
research shows that the benefits of the bacterium e. coli can not when evolved resistance
to clinical levels of antibiotics.
"It is often said that Darwinian evolution is slow, but nothing could be further from
reality, especially when exposed to the bacterium against antibiotics. The bacteria have an
uncanny ability to re-arrange their DNA and this can stop the drug works, sometimes in a
matter of days. While the rapid changes of DNA can be harmful to human cells, bacteria can
have some benefits, as long as they arrive at the appropriate changes. "
The team is investigating the effect of the antibiotic doxycycline in DNA from e. coli.
After repeated exposure to drugs, bacteria that evolve into resistant mutant form of
features such as the ability to pump the antibiotic outside their cells. Other changes are
likely to see changes in the bacteria from the surface of the occupiers "biofilms" body
adapted to run through the bloodstream.
Co-author Dr. Carlos Reding said: "look at biofilms in a dirty sink when you look in vain."
"But our study used a liquid condition, a bit like blood circulation, so that e. coli can
leave his lifestyle from the biofilm support increased production of cells."
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